Genesis 50:23
(23) The third generation.--These would be Joseph's great-grandchildren. Thus Eran, son of Shuthelah, son of Ephraim, was to be born in Joseph's lifetime (Numbers 26:35-36).

Were brought up . . . --Heb., were born upon Joseph's knees, that is, were adopted by him. (See Note on Genesis 30:3.) They would not form tribes, as this prerogative was reserved for the sons of Jacob (Genesis 48:5), but they would count as Joseph's sons (Genesis 48:6), and form "families."

Verse 23. - And Joseph saw Ephraim's children of the third generation: - i.e. Ephraim's great-grandchildren (Kalisch, Lange), or Ephraim s great-great-grandsons (Keil, Murphy), which perhaps was not impossible, since Ephraim must have been born before Joseph's thirty-seventh year, thus allowing at least sixty-three years for four generations to intervene before the patriarch's death, which might be, if marriage happened early, say not later than eighteen - the children also of Machir the son of Manasseh-by a concubine (1 Chronicles 7:14) were brought up upon Joseph's knees - literally, were born upon Joseph's knees, i.e. were adopted by him as soon as they were born (Kalisch, Wordsworth, 'Speaker's Commentary'), or were born so that he could take them also upon his knees, and show his love for them (Keil).

50:22-26 Joseph having honoured his father, his days were long in the land, which, for the present, God had given him. When he saw his death approaching, he comforted his brethren with the assurance of their return to Canaan in due time. We must comfort others with the same comforts with which we have been comforted of God, and encourage them to rest on the promises which are our support. For a confession of his own faith, and a confirmation of theirs, he charges them to keep his remains unburied till that glorious day, when they should be settled in the land of promise. Thus Joseph, by faith in the doctrine of the resurrection, and the promise of Canaan, gave commandment concerning his bones. This would keep up their expectation of a speedy departure from Egypt, and keep Canaan continually in their minds. This would also attach Joseph's posterity to their brethren. The death, as well as the life of this eminent saint, was truly excellent; both furnish us with strong encouragement to persevere in the service of God. How happy to set our early in the heavenly race, to continue stedfastly, and to finish the course with joy! This Joseph did, this we also may do. Even when the pains of death are upon us, if we have trusted in Him upon whom the patriarchs, prophets, and apostles depended, we need not fear to say, My flesh and my heart faileth, but God is the strength of my heart, and my portion for ever.And Joseph saw Ephraim's children of the third generation,.... His great grandchildren's children; and which shows, as most interpreters observe, that Jacob's prediction, that Ephraim should be the greatest and most numerous, very early began to take place:

and the children also of Machir, the son of Manasseh, were brought up upon Joseph's knees; Machir had but one son by his first wife, whose name was Gilead; but marrying a second wife, he had two sons, Peresh and Sheresh; see 1 Chronicles 7:14 who might be born before the death of Joseph, and be said to be brought up upon his knees, being educated by him, and often took up in his lap, and dandled on his knees, as grandfathers, being fond of their grandchildren, are apt to do.

Genesis 50:22
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